Multiple sclerosis in a young patient: diagnostic challenge in the post-covid 19 context.
DOI:
https://doi.org/10.62059/bz6gbn02Keywords:
Multiple sclerosis, Demyelination, Spastic paraparesis, magnetic resonance imaging, oligoclonal bands, cerebrospinal fluidAbstract
A previously healthy 40-year-old man presented with progressive lower limb weakness, accompanied by paresthesias and gait disturbances, following an infection with the SARS-CoV-2 virus. Symptoms partially resolved without the need for hospitalization or immunomodulatory treatment. Three years later, the patient experienced a new neurological relapse characterized by spastic paraparesis, hyperreflexia, Achilles clonus, and gait ataxia with postural instability. Brain and spinal magnetic resonance imaging revealed hyperintense lesions on T2-weighted and FLAIR sequences, with some showing contrast enhancement, suggesting dissemination in space and time. Cerebrospinal fluid analysis showed positive oligoclonal bands with normal glucose and protein levels. Based on the McDonald criteria, a diagnosis of relapsing-remitting multiple sclerosis was established, and treatment with intravenous corticosteroids and disease-modifying therapy was initiated. This case highlights the importance of early and accurate diagnosis of demyelinating disorders, particularly in the context of potential viral triggers such as SARS-CoV-2.References
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Copyright (c) 2026 Andres Hernández Navas, Luis Dulcey Sarmiento, Jaime Gómez Ayala, Juan Therán León (Autor/a)
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