Use of different pulp devitalizers during endodontic treatment
DOI:
https://doi.org/10.62059/LatArXiv.preprints.418Keywords:
Depulpin, Pulpectomies, Pulpotomies, Pulp devitalizers, EndodonticsAbstract
Introduction: Depulpin stands out as a devitalizing agent without arsenic, since its application is easy and safe with analgesic and disinfectant properties. Although it has antimicrobial and mummifying benefits, its use can cause tissue intolerance. The use of paraformaldehyde and the initial irritation of eugenol are questioned. MTA and Biodentine are considered effective options in vital pulp therapies. The objective is to evaluate the effectiveness and benefits of Biodentine, MTA and Depulpin.Materials and methods: 3 articles were selected and reviewed in their entirety along with their main findings. Results: In the first study with 536 patients, the effectiveness of Depulpin, arsenic deactivating agents and paraformaldehyde devitalizing
agents was compared. Depulpin demonstrated an efficacy of 88.9%, outperforming the other options. Biodentine™ showed greater cell proliferation than MTA Angelus™. Biodentine™ also favored cell migration and fixation, standing out in biocompatibility compared to other materials such as Theracal LC and IRM™. Discussion: Depulpin with paraformaldehyde stands out for being safe and less toxic than arsenic, offering effective pulp devitalization. Biodentine and MTA are biocompatible, with Biodentine setting faster. Both promote cell growth. Arsenic relieves pain, but is highly toxic. Alternatives like IRM™ and Theracal LC present challenges. MTA and Biodentine are recommended, as they offer efficacy, safety and biocompatibility in pulp devitalization. Conclusion: Biodentine, Depulpin and MTA are the best biocompatible materials for root canal treatment.
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Copyright (c) 2025 Shesenya Bravo, Ana del Carmen Armas , Jeannet Patricia López Yánez , Maria Cristina Rockenbach (Autor/a)
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